Checking In With Progress On The MTHFR Journey

Let’s check in with what is going on so far. If you’ve been following the process this season, you will have noticed that I haven’t really addressed what we’re doing in a while, so let’s touch base.

There are some reasonably long stretches in the MTHFR journey in which we aren’t really changing things, doses are just staying the same, and it might seem like not much is happening. The reality, in fact, is that lots of things are happening in your body but none of it needs additional input from you.

This phase of the journey is what I like to call “Burning Through The Backlog.” When you first start diet changes and methyl folate or SAMe or whatever workaround you’re using, you see the immediate activation of the methyl cycle and some immediate health changes. Usually, that feels like a better mood, less anxiety, etc… After that initial balancing phase, the progress slows down but it isn’t because your body has stopped doing things.

This part of the process involves unpacking your body’s to-do list. All of the things it couldn’t do in the past because methylation just wasn’t happening fast enough. It’s a time of more subtle change where neurotransmitters are slowly coming into balance, toxins are slowly being eliminated, inflammation is slowly decreasing and oxidative stress is balancing out. Even your hormones and energy levels are being influenced in this process

How To Make Sure You’re Burning Through The Backlog Efficiently – Check Your Basics

In this phase, it’s easy to forget some of the basics so the first thing I want you to do this week is to take a look at things you should be doing and tighten up where needed.

  • Folic Acid – Make sure folic acid is out of your diet and supplements and isn’t creeping back in without you noticing.
  • Balanced Diet With Natural Folates – Get lots of fruits and veggies, as much fiber as you can pack in, moderate protein, and plenty of good food sources of natural folate like lentils, black beans, spinach, asparagus, dark green leafies, avocados, marmite, and any kind of bean or pea you feel like eating.
  • Multivitamin – Keep up with the background of other B vitamins – this is usually in the form of a good basic multivitamin. All of the processes that are happening now, from neurotransmitter formation to detoxification, to energy production, to balancing your oxidative stress and reducing inflammation needs a good solid basis of all the B vitamins.
  • Sleep and Rest – I really enjoy the paradox presented by this particular issue. Most of my clients say they would love more sleep and rest, but it’s always the hardset possible thing to actually accomplish. Just keep trying to work actual sleep and actual rest into your schedule.
  • Moderate Exercise – because generally, MTHFR folks do best with regular exercise, but not extreme exercise. Ironically, there are lots of us who are professional athletes and serious competitive athletes, but for those people it’s important to make sure methylation is balanced and to compensate adequately for the extra damage being done to their bodies.
  • Detox Support – since detoxification is such a huge part of Burning Through The Backlog, it’s important to give your body the support it needs. This can be in the form of gentle detox teas, castor oil topically, sweating it out, extra dietary fiber, or some mish-mash of all of these things. We’ve done posts on detox support before as well.

Burning Through The Backlog Efficiently – Optimizing Your Dose Of Methylation Drivers

The supplement or supplements you’re taking that specifically support methylation should be dose-checked occasionally. Maybe quarterly in this whole process. This could include any one of the following supplements:

  • 5-LMTHF or another form of methylated folate
  • Folinic Acid
  • SAMe

These supplements are all pushing the methylation cycle forward and so may need an occasional check-in to see if you’re still on the right dose. Usually, this means trying to increase your dose to see how you feel.

Generally, in this process, you increase by the smallest increment you can and make sure you’re using your symptom tracker for a couple of weeks before and after so you can see if there are small changes that you might not notice otherwise. If you feel fine with the higher dose, that’s great. Keep using the higher dose unless you start to get symptoms that indicate that your dose is too high. If you get symptoms right away or within the first two weeks then go back to your original dose.

Symptoms That Your Dose Is Too High

Typically too high a dose of anything that drives methylation feels hyper-caffeinated. It’s anxious, restless, can’t settle down, fidgetty, has a racing heart, or feels like all-out panic. If you’re noticing any of that – even if it’s a small change, then your balance will be better with a slightly smaller dose.

What About Other Supplement Routines?

For some people, taking supplements that take an alternate route through the methylation pathway, rather than methylation drivers, is the best path forward. Especially if you’re starting out from a kind of messy health place. These are supplements like methionine or choline. Methionine just gives you more of the raw ingredients to make SAMe and choline cuts through the middle of the methylation cycle as a viable short-term work around. These are great band-aids, but probably not the thing you want to be relying on for the long-term. If you are looking for long-term solutions but really can’t manage any of the true methylation drivers – methylfolate, SAMe, or folinic acid – then choline is the better of these two options. You still need the other B vitamins, and as much natural dietary folate as you can manage.

Moving forward, it’s a good idea to check in with your body quarterly to see if your dose is sufficient or if you’re getting enough for your body’s needs right now. Your dose will always be somewhat dynamic. Eventually, you will actually catch up with all of the things on your body’s internal to-do list and need a far lower dose, so watch for those anxious/hyper symptoms and keep it on your radar that your best dose might need to decrease too.

Thank you so much for listening today and give some thought to joining us in Genetic Rockstars – the MTHFR community. This month we’re talking about some of the links between MTHFR and histamine, and it’s a great way to meet people who understand what you’re going through and who have great information to share.

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Empty Bucket, Fix Backlog.

I feel like this is getting into Zen slogan territory – Chop wood, carry water… Empty bucket, fix backlog. Actually, for us MTHFR folks, this could be tantamount to a personal mantra guiding us through life.

Emptying Your Bucket

Your bucket, you’ll remember, is all of the stuff that is happening to you right now. It’s anything ongoing that your body is dealing with. It includes lots of things that happen all the time in the background, a few things that you can change or modify, and the rest we can just chalk up to life.

  • Metabolism of food
  • Daily maintenance of oxidative balance, hormone levels, fluid balance, neurotransmitters, and all the amazing things your body does without you being aware.
  • Healing, cell turnover, and cell regeneration.
  • Immune defenses against viruses, bacteria, molds, fungi, yeast, parasites, and other pathogens,
  • Pollutants in the air, water, food, self-care products
  • Food additives – artificial colors, flavors, sweetness, preservatives, etc… (fixable)
  • Ingested Irritants – especially food sensitivities (fixable)
  • Dehydration (fixable)
  • Nutritional deficiencies (fixable)
  • Lack of sleep (fixable)
  • Sedentary lifestyle, work, or habits (fixable)
  • Too much UV exposure (fixable)
  • Work, family, and life stress (life)
  • Big changes – moving, marriage, births, deaths, new pets, new jobs, loss of jobs, financial changes, relationship changes (also life)

This part of the Empty Bucket, Fix Backlog mantra comes down to making conscious decisions about your health. This is the 99.9% of healthcare that has nothing to do with your doctor and everything to do with the decisions you make throughout the day. Will you have the extra helping of mac and cheese? Another martini? Two more hours of TV at night? Another glass of water? This is the part that is entirely under your control (and often feels entirely out of control).

It comes down to valuing your health over the momentary pleasure you’re going to get from that bag of chips or the candy bar in the checkout line, and also knowing that if you make decisions that prioritize your health 90% of the time, the other 10% can slide. There is and always has to be room to be human.

Bear in mind an optimal diet has lots of room for treats, you just have to know what is a treat your body can handle vs. one that triggers the worst for you. This is where working with a great practitioner, health coach, or ideally a healing group on the same journey, like Genetic Rockstars where you can get help from a group of peers to stay on track.

In terms of biggest-impact changes, for MTHFR folks, balancing methylation is always the biggest because that is the heart of the problem with the MTHFR mutation. After that, eliminating food sensitivities and working on your sleep have the biggest and most pervasive impact on your health.

Fixing Your Backlog

Your backlog is stuff that used to be in your bucket that your body didn’t have the resources to deal with at the time. The only safe way for your body to handle something that it doesn’t have the resources to address at that moment is to store it, wall it off, isolate it, and otherwise keep it away from vital tissues. This isn’t ideal – your body would rather eliminate it completely, but sometimes that isn’t an option. For MTHFR folks who haven’t had good methylation balance, it may not have been an option to deal with lots of things for a very long time.

What I’m really saying here is that we MTHFR folks have a lot of baggage. 😂

Your backlog may contain:

  • Heavy metals
  • Hormones you couldn’t process
  • Plasticizers, pesticides, herbicides
  • Synthetic fragrances, parabens, petroleum products
  • Persistent organic pollutants
  • Tissue repair/remodeling
  • Sleep deficit
  • Unaddressed cell regulation (this can be destroying cells that are dysregulated or cell regeneration)
  • Chronic or subclinical infections of any type
  • Chronic inflammatory processes
  • Genetic repair

You may have spotted a couple of big differences between your bucket and your backlog here. One is that your bucket is filled with things you’re aware of (mostly). These are stressors that you probably recognize and have some awareness of. Your backlog, on the other hand, is mostly made up of things you don’t know about at all. They were once in your bucket, but they passed through the bucket a long time ago. Another big difference is that nothing in the backlog is under any kind of conscious control. Even addressing the backlog is unconscious – your body will do it when it’s ready and has resources, but it’s not really your brain’s decision.

What I’m saying here is that we MTHFR folks have a lot of baggage. 😂

Amy, mutant-in-chief at Genetic Rockstars.

This means there is nothing you can really do to encourage the processing of your backlog. In good news, your body will happily get to it as soon as it has some resources available so balancing your methylation is also the biggest and most important step here.

If there is anybody reading or listening who is thinking, “Ok, Amy, but what do I actually have to do to balance my methylation?” Here’s the super quick and dirty.

  1. Join Genetic Rockstars so you have the support of other people who are on the same journey.
  2. Eliminate folic acid from your diet – this is fortified foods like wheat and sometimes corn products, and also from your supplements first thing.
  3. Add good food sources of natural folate – things like beans, avocados, asparagus, fresh-squeezed orange juice, and marmite.
  4. Begin with a background of other B vitamins without folate or B12
  5. Add a B12 that suits you
  6. Add 5-LMTHF, SAMe, or another methylation driver
  7. Adjust as needed.

That is really the crux of it! I can’t wait to see you in Genetic Rockstars.

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Obstacles with MTHFR – The Bucket and The Backlog

The MTHFR journey to health can be a bumpy one and there are certainly ups and downs along the way. We have talked a bit about this progression before, but I want to clarify the bumps in the road.

Moving toward health with MTHFR can feel really up and down – like you make progress for a little while and then hit a wall. But why? What are these walls and where do they come from? In my opinion, they come from two places. Your bucket, and your backlog.

Your Bucket

We’ve talked about the bucket before – your bucket is unique to you and it represents a container for how many stressors your body can hold before it fills up and symptoms start to spill over. The goal with any form of healing, not just with MTHFR, is to empty out your bucket so that your body has more room to deal with stressors.

So your bucket really is the stuff that is coming in right now – it’s stressors that are actively having an effect on your body. This could be viruses or pathogens, it could be alcohol, it could be inhalants from the perfume aisle or your big deadline at work. It could be a night of bad sleep, food that caused inflammation, or even an injury. This is whatever is actively being dealt with by your body in this very moment.

Your Backlog

Your backlog, on the other hand, is the stuff that needs doing that has accumulated over the years. This could be accumulated toxins that your body didn’t have the resources to process at the time they came in. It could be sleep debt, long-term hormonal imbalance, chronic inflammation, chronic oxidative stress, long-term blood sugar changes, or nutritional deficiencies. These are the big-picture things that your body isn’t quite keeping up with.

Backlog is really easy to picture as the baggage your body has to carry around with it on a day to day basis. You might not be actively adding to it right this second, but your body would like to be able to put some of it down.

It helps to think of your backlog as your body’s long-term to-do list. This is stuff that needs to be done and your body is just waiting on the resources it needs, then it will crack into this in a hurry.

So Why Do Bucket and Backlog Make Healing Bumpy?

The main thrust of working with MTHFR is working to balance your methylation, and that means adding resources, like methyl folate, that your body might not have had in a while (or, ahem… ever).

When we add these resources it suddenly allows for all of this work to start happening and your body gets really excited that it can clear up some of the junk it’s been holding on to, and there can be a bit of a flood at the gates, so to speak. Your body starts working through the to-do list but this takes both energy and resources.

If you happen to be having a full bucket day (more stressors than usual) or a busy backlog day (more processing than usual) it can feel like you’re hitting a wall or like your symptoms are worse.

Fixing the Bad Days

I know everyone wants a picture of healing that doesn’t have any bad days in it, but unless you can move to an ashram or a spa in thailand and devote yourself entirely to healing for the next year, it isn’t realistic to expect it to progress smoothly upward. There are going to be some bumps because real life happens.

Bumps are ok as long as you have a toolkit to deal with them. Here are a few suggestions:

  • Keep your bucket clean – really try to limit your bad days by minimizing what is coming in right now. This means you should get rid of:
    • Toxin exposure as much as possible.
    • Food sensitivities
    • Folic Acid (synthetic) in your diet and supplements
    • Excess alcohol
    • Tobacco
  • Sleep – getting good sleep gives your body that time to help clean house, recharge, and prepare for more work. If sleep is difficult, read more here
  • Watch your diet – good nutrition gives your body the resources it needs to deal with the bucket and the backlog.
  • Boost your antioxidants – if you’ve had a lot of stuff coming up lately or if you feel like you’re hitting a wall and having more symptoms, it can be a good idea to boost antioxidants or try different antioxidants to help your body cope with the excess.
  • Rest – rest is actually a different thing than sleep and your body needs both. Take some downtime to recharge mentally and physically, especially when you’re having a low day.
  • Use your gentle detox strategies – if your body is mired in the backlog, help it out with detoxification support that will move the process forward and help clear up the symptoms you’re experiencing. These include:
  • Be patient. Getting through the backlog takes time, energy, and patience and you will start feeling better from day one, but it will take time to work out all of the kinks.
Starting methylfolate can be rough, but things smooth out with time.

Bad days aren’t the most fun thing in the world, but they are a good signal that your body needs more support. If you haven’t been using a symptom tracker, I highly recommend starting today because your detoxification symptoms have a particular pattern and if you can recognize them, then you can begin to deal with them appropriately when they arise. This saves a lot of fuss and bother in the long run.

Also, you’ll begin to see patterns emerging that could give you more information about the way your body is dealing with certain foods, sleep, hormones, and other stressors. Symptom tracking makes all the difference.

If you don’t have a symptom tracker, you can download one for free by signing up for my email list (below or on the right-hand side of your screen) or you can find it in the MTHFR library in Genetic Rockstars, the entirely free MTHFR healing community.

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