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S2E31: COMT Fast

Low Estrogen and Stress Hormones with COMT fast

The COMT fast picture, as you can imagine, is the flip-side of COMT slow. This enzyme works too well, eliminating crucial substances before they have the chance to act. The most well-researched polymorphism that contributes to this picture is the…

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S2E30: Slow COMT

Symptoms and signs of slow COMT

This week, let’s talk about our first of two COMT pictures. COMT slow. Remember, this means the COMT enzyme is less efficient than normal so the catecholamines it is supposed to break down stay in circulation longer. This leads to…

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S2E28: COMT and MTHFR.


To kick off our series on other polymorphisms, I’m starting with another heavy-hitter that is deeply entwined with MTHFR.  This polymorphism is also in a gene that codes for an enzyme by the name of catechol-O-methyltransferase. I’m hoping that right…

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