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Understanding the Interaction Between MTHFR and Slow COMT Gene Variants
With MTHFR and slow COMT, you may produce neurotransmitters inefficiently (MTHFR), but also break them down slowly (COMT). This can lead to fluctuating dopamine levels, periods of overstimulation or underperformance, and increased sensitivity to small biochemical changes.

Dr. Amy Neuzil, Methylation and MTHFR Expert
5 days ago6 min read


MTHFR Symptoms in Children: A Guide for Parents
MTHFR is one of those topics that can send parents down a rabbit hole very quickly. A child has anxiety, allergies, ADHD symptoms, food sensitivities, a tongue-tie, a sacral dimple, or a “sugar bug” vein between the eyes, and suddenly the internet says: “It’s MTHFR.”
While it may be MTHFR, the truth is far more nuanced and definitely less scary.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Jul 96 min read


Norepinephrine and Methylation - Could Norepinephrine Symptoms Be a Clue to Methylation Status?
Two human figures made of glowing wires and neor representing Norepinephrine and methylation. Norepinephrine is both a neurotransmitter in the brain and a hormone in the body, and more importantly, symptoms of low or high norepinephrine could tell us something about methylation patterns.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Jul 25 min read


MTHFR and the Gallbladder
MTHFR and the gallbladder are linked, but not directly. Bile production and gallbladder function are deeply connected to liver metabolism, nutrient status, phospholipid production, inflammation, cholesterol balance, and methylation. That means common MTHFR gene variants may influence gallbladder health indirectly, not because MTHFR “controls the gallbladder,” but because methylation helps support several biochemical pathways that make healthy bile possible.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Jun 256 min read


Is There a Link Between MTHFR, Methylation, and ADHD?
In clinical practice, however, patterns often emerge before the research fully catches up. One such pattern I observe is a striking overlap between individuals with MTHFR gene variants and symptoms of ADHD or ADD. To be clear: this is not yet a fully established causal relationship. But there is enough emerging evidence—and strong biochemical plausibility—to warrant a closer look.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Jun 185 min read


MTHFR and Food Sensitivities with Elimination Diet Guidelines
The MTHFR gene mutation has gained attention for its potential role in various health issues, including food sensitivities. Understanding this connection can help individuals manage symptoms more effectively. This post explains how the MTHFR mutation may influence food sensitivities and provides clear steps for conducting an elimination and challenge diet to identify problematic foods.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Jun 45 min read


Normal Weight Obesity and MTHFR
Normal weight obesity (NWO) is a health condition that often goes unnoticed because it hides behind a normal body weight. People with NWO have a body mass index (BMI) within the normal range but carry excess body fat, especially around the abdomen. This post explores normal-weight obesity and MTHFR gene variants, and how these two are linked.

Dr. Amy Neuzil, Methylation and MTHFR Expert
May 284 min read


Understanding MTHFR and MAOA: A Deep Dive into Your Genetics
If you’ve been exploring your genetics, you may already be familiar with the MTHFR gene and its role in methylation. But if you also carry a slow MAOA variant, it adds an entirely different layer—one that directly impacts mood, stress response, and neurotransmitter balance. MTHFR and slow MAOA must be optimized together to avoid making symptoms worse.

Dr. Amy Neuzil, Methylation and MTHFR Expert
May 215 min read


Naturally Boost GLP-1 for MTHFR Gene Mutation Support
People with the MTHFR gene mutation often face challenges related to methylation and metabolic health. One promising area of support involves increasing levels of glucagon-like peptide-1 (GLP-1), a hormone that helps regulate blood sugar, appetite, and insulin secretion. It is possible to naturally boost GLP-1 levels for MTHFR gene mutation support and weight reduction.

Dr. Amy Neuzil, Methylation and MTHFR Expert
May 144 min read


How to Manage Both MTHFR and PEMT Gene SNPs
PEMT quietly works alongside MTHFR, and when both are affected, the impact on health can be much more significant. MTHFR and PEMT must be managed together to avoid consequences to fertility, liver function, neurotransmitters, and more.

Dr. Amy Neuzil, Methylation and MTHFR Expert
May 74 min read


Understanding GLP-1 and MTHFR Gene Variance
GLP-1 inhibitors have gained attention in recent years for their role in managing blood sugar levels and supporting weight loss. But what exactly is GLP-1, how do these inhibitors work in the body, and what happens when they interact with genetic factors like the MTHFR gene variance? This article breaks down these questions with clear explanations and insights from peer-reviewed research.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Apr 305 min read


Coffee for MTHFR Gene Mutation and Methylation: Benefits and Drawbacks
Coffee is one of the most widely consumed beverages worldwide, praised for its stimulating effects and rich flavor. For individuals with an MTHFR gene mutation, however, coffee consumption may have unique implications.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Apr 234 min read


Glycine and MTHFR Gene Mutation: Methylation, Glutathione, and Sleep Enhancements
People with the MTHFR gene mutation often face challenges related to methylation, oxidative stress, and sleep quality. Glycine, an amino acid found in both food and supplements, plays a crucial role in addressing these issues. Glycine for MTHFR can act as a methyl balancer, which is crucial for good health.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Apr 163 min read


Navigating MTHFR Diet Restrictions: Foods to Avoid with MTHFR Mutation
Living with an MTHFR gene mutation can feel like stepping into a complex world of health advice and dietary rules. I get it - it’s overwhelming at first. But understanding what to eat and, just as importantly, what to avoid can make a huge difference in how you feel every day.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Apr 95 min read


Choosing the Best B12 for MTHFR Mutation: Exploring Your MTHFR B12 Options
If you’ve been navigating the world of MTHFR gene mutations, you might have come across a lot of confusing information about vitamins, especially vitamin B12. It’s a crucial nutrient, but not all B12 supplements are created equal—especially when it comes to supporting your unique genetic makeup. Today, I want to walk you through the best ways to choose the right B12 for your MTHFR mutation, so you can feel confident and empowered in your health journey.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Apr 25 min read


Discover the Best Diet for MTHFR Mutation
Living with an MTHFR mutation can feel overwhelming at times. You might be wondering how to support your body better, especially through your diet. The good news? You can take meaningful steps today to nourish your body and help balance your methylation process. Let’s explore together the best diet for MTHFR mutation and how simple food choices can make a big difference.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Mar 264 min read


How to Find an Online MTHFR Health Coach
Living with an MTHFR gene mutation or methylation imbalance can feel overwhelming. You might be searching for answers, feeling tired, or struggling with symptoms that don’t seem to improve. That’s where an MTHFR health coach can make a real difference. But how do you find the right support, especially online? Let me walk you through the process so you feel confident and empowered every step of the way.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Mar 255 min read


Identifying MTHFR Symptoms in Females: What You Need to Know
If you've been feeling off lately, struggling with unexplained fatigue, mood swings, or other hormone imbalances, you might be wondering if there’s a deeper cause. One possibility that often goes unnoticed is an MTHFR gene mutation, because MTHFR symptoms in females can present differently than they do in males.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Mar 194 min read


MTHFR and Inflammation, plus Strategies for Relief
Inflammation is a natural response by the body to injury or infection, but when it becomes chronic, it can contribute to many health problems. One factor linked to higher resting levels of inflammation is a genetic variation in the MTHFR gene. This post explores why MTHFR mutations may increase inflammation, reviews current research, and offers practical strategies to reduce inflammation naturally.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Mar 124 min read


Choline for MTHFR and Methylation: Understanding Types, Food Sources, and Health Benefits.
Choline is an essential nutrient that plays a vital role in brain function, liver health, and cellular metabolism. For people with the MTHFR gene mutation or methylation imbalances, understanding choline’s different forms, food sources, and health benefits becomes even more important.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Mar 54 min read
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