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MTHFR mutation
MTHFR gene mutation information, resources, and ideas to live a healthier life.


The Critical Role of Zinc in Supporting Methylation for Individuals with MTHFR Gene Mutations
Understanding the role of zinc in supporting methylation can help those with MTHFR mutations improve their methylation balance and overall well-being.

Dr. Amy Neuzil, Methylation and MTHFR Expert
8 hours ago4 min read


Understanding MTHFR and Homocysteine Testing: When Numbers Matter for Blood Clot Risk
The connection between MTHFR gene mutations and blood clot risk often centers on homocysteine levels. The common story goes like this: if you have an MTHFR mutation, your homocysteine will be high, and that means you face a greater risk of blood clots. But this narrative oversimplifies a complex relationship.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Nov 174 min read


Brain Fog and Blood Sugar and the Link to MTHFR
Brain fog is a frustrating symptom that many people experience without fully understanding its causes. It often feels like a cloud over your thinking, making it hard to focus, remember details, or process information clearly. One key factor linked to brain fog is blood sugar instability. When blood sugar levels swing too high or too low, the brain struggles to function optimally. Another important piece of this puzzle is the MTHFR gene variance, which can influence how the bo

Dr. Amy Neuzil, Methylation and MTHFR Expert
Nov 74 min read


High Folate Levels as a Warning Sign for MTHFR Dysfunction and the Risks of Unmetabolized Folic Acid
When you receive blood test results showing high folate levels, it might seem positive at first. However, it can signal a potential issue with MTHFR (methylenetetrahydrofolate reductase) function and highlight risks related to unmetabolized folic acid (UMFA) buildup in the bloodstream.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Oct 304 min read


Highly Sensitive Person, or HSP, Neurology and Genetics.
Highly Sensitive People (HSPs) often experience the world differently than others. This unique trait can manifest in various ways, from heightened emotional responses to an acute awareness of sensory stimuli. Understanding the neurological and genetic underpinnings of HSP can help individuals identify these traits in themselves and navigate their sensitivities more effectively.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Oct 94 min read


Folate Levels and Sun Exposure - What You Need To Know.
Sunlight and folate have a complicated relationship, and new research has showed that the more UV exposure you have, the lower your red blood cell folate levels will be. Protect your folate status this summer!

Dr. Amy Neuzil, Methylation and MTHFR Expert
Jul 253 min read


Methylation Adaptogens
You may have heard the term "adaptogens" in regards to adrenal health. These seemingly miracle substances help your body to adapt - either increase or decrease your stress hormone production depending on your need and baseline status. It turns out, there are adaptogens in other realms as well, and one of the most important could be methylation adaptogens.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Jun 24 min read


MTHFR and Marijuana Use
There are a number of both risks and potential therapeutic effects that are worth considering with MTHFR and any form of medical or non-medical cannabis use. The primary considerations are addiction and addictive tendencies, medical risks for MTHFR specifically, and also cannabis and its derivatives as methylation adaptogens.

Dr. Amy Neuzil, Methylation and MTHFR Expert
May 263 min read


The Artist and The Activist Personality Type
Methylation imbalance shows itself in four personality types that can help you predict how you might react to different supplements and...

Dr. Amy Neuzil, Methylation and MTHFR Expert
Apr 244 min read


The Achiever and The Athlete Personality Type
Methylation imbalance shows itself in four personality types that can help you predict how you might react to different supplements and...

Dr. Amy Neuzil, Methylation and MTHFR Expert
Feb 243 min read


Discover Your Methylation Archetype: Achiever, Artist, Athlete, or Activist?
Which Methylation Personality Describes You Best? Methylation imbalance, often caused by MTHFR gene mutations, excessive intake of...

Dr. Amy Neuzil, Methylation and MTHFR Expert
Feb 124 min read


Gentle Six-Week Detoxification Protocol for MTHFR
When you have an MTHFR polymorphism, detoxification can be difficult. Gentle detox, like the one in this protocol, has many benefits including weight loss, better energy, more balanced blood sugars, reduced toxic burden, better skin, and better sleep.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Jul 9, 20246 min read


What Are The Risks of High Dose Folic Acid and What is The Maximum Safe Dose of L-5MTHF?
L-5MTHF is the active form of folate, but ironically, it is far less studied than the synthetic (inactive) form folic acid. Because of that, the safe upper limit of L-5MTHF is not known precisely, but we can draw some conclusions from existing data about the risks of high-dose folic acid.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Apr 11, 20246 min read


Detox Basics
Detox is easy to get wrong - even for practitioners. So here are some of the basic foundations to good, effective, ongoing detoxification.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Mar 22, 20244 min read


What is Methylation?
Methylation is a very small, foundational chemical function in your body. It involves the moving of a methyl group, which is a carbon with three hydrogens that you can picture a lot like a Mickey Mouse head with an extra ear (shudder).

Dr. Amy Neuzil, Methylation and MTHFR Expert
Nov 20, 20234 min read


Castor Oil for MTHFR
Castor oil has, in fact, been used for thousands of years and was considered so valuable it was included in the tombs of ancient Pharos in Egypt as early as 4,000 B.C.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Nov 8, 20235 min read


What Is Sleep For?
Sleep is one of our basic biological functions. We'll talk about what it is, what it's for, and also 8 keys to a healthy sleep cycle.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Nov 2, 20236 min read


If You're Tired, Try This First.
If you're tired all the time, here are some factors to rule out at home or with your doctor.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Sep 22, 20236 min read


What is Fatigue, And Why Does Everyone Have It?
Fatigue, which is a feeling of extreme tiredness, weakness, or exhaustion, is the first symptom of almost every medical problem, including MTHFR. It can be linked to almost every body system, and it is the most general symptom we have. It is also linked to a number of common gene SNPs, including MTHFR, fast MAOA, fast COMT, and more. It is tied to lifestyle factors like diet, nutrition, sleep, and stress. So, actually, in light of all of that, it is surprising any of us don't

Dr. Amy Neuzil, Methylation and MTHFR Expert
Sep 18, 20235 min read
MTHFR and Migraine
As with so many other conditions, the research shows that people with the MTHFR gene mutation are more likely to have migraines....

Dr. Amy Neuzil, Methylation and MTHFR Expert
Aug 11, 20234 min read
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