top of page

MTHFR mutation
MTHFR gene mutation information, resources, and ideas to live a healthier life.


High Folate Levels as a Warning Sign for MTHFR Dysfunction and the Risks of Unmetabolized Folic Acid
When you receive blood test results showing high folate levels, it might seem positive at first. However, it can signal a potential issue with MTHFR (methylenetetrahydrofolate reductase) function and highlight risks related to unmetabolized folic acid (UMFA) buildup in the bloodstream.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Oct 30, 20254 min read


Highly Sensitive Person, or HSP, Neurology and Genetics.
Highly Sensitive People (HSPs) often experience the world differently than others. This unique trait can manifest in various ways, from heightened emotional responses to an acute awareness of sensory stimuli. Understanding the neurological and genetic underpinnings of HSP can help individuals identify these traits in themselves and navigate their sensitivities more effectively.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Oct 9, 20254 min read


Folate Levels and Sun Exposure - What You Need To Know.
Sunlight and folate have a complicated relationship, and new research has showed that the more UV exposure you have, the lower your red blood cell folate levels will be. Protect your folate status this summer!

Dr. Amy Neuzil, Methylation and MTHFR Expert
Jul 25, 20253 min read


Methylation Adaptogens
You may have heard the term "adaptogens" in regards to adrenal health. These seemingly miracle substances help your body to adapt - either increase or decrease your stress hormone production depending on your need and baseline status. It turns out, there are adaptogens in other realms as well, and one of the most important could be methylation adaptogens.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Jun 2, 20254 min read


MTHFR and Marijuana Use
There are a number of both risks and potential therapeutic effects that are worth considering with MTHFR and any form of medical or non-medical cannabis use. The primary considerations are addiction and addictive tendencies, medical risks for MTHFR specifically, and also cannabis and its derivatives as methylation adaptogens.

Dr. Amy Neuzil, Methylation and MTHFR Expert
May 26, 20253 min read


The Artist and The Activist Personality Type
Methylation imbalance shows itself in four personality types that can help you predict how you might react to different supplements and...

Dr. Amy Neuzil, Methylation and MTHFR Expert
Apr 24, 20254 min read


The Achiever and The Athlete Personality Type
Methylation imbalance shows itself in four personality types that can help you predict how you might react to different supplements and...

Dr. Amy Neuzil, Methylation and MTHFR Expert
Feb 24, 20253 min read


Discover Your Methylation Archetype: Achiever, Artist, Athlete, or Activist?
Which Methylation Personality Describes You Best? Methylation imbalance, often caused by MTHFR gene mutations, excessive intake of...

Dr. Amy Neuzil, Methylation and MTHFR Expert
Feb 12, 20254 min read


Gentle Six-Week Detoxification Protocol for MTHFR
When you have an MTHFR polymorphism, detoxification can be difficult. Gentle detox, like the one in this protocol, has many benefits including weight loss, better energy, more balanced blood sugars, reduced toxic burden, better skin, and better sleep.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Jul 9, 20246 min read


What Are The Risks of High Dose Folic Acid and What is The Maximum Safe Dose of L-5MTHF?
L-5MTHF is the active form of folate, but ironically, it is far less studied than the synthetic (inactive) form folic acid. Because of that, the safe upper limit of L-5MTHF is not known precisely, but we can draw some conclusions from existing data about the risks of high-dose folic acid.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Apr 11, 20246 min read


Detox Basics
Detox is easy to get wrong - even for practitioners. So here are some of the basic foundations to good, effective, ongoing detoxification.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Mar 22, 20244 min read


What is Methylation?
Methylation is a very small, foundational chemical function in your body. It involves the moving of a methyl group, which is a carbon with three hydrogens that you can picture a lot like a Mickey Mouse head with an extra ear (shudder).

Dr. Amy Neuzil, Methylation and MTHFR Expert
Nov 20, 20234 min read


Castor Oil for MTHFR
Castor oil has, in fact, been used for thousands of years and was considered so valuable it was included in the tombs of ancient Pharos in Egypt as early as 4,000 B.C.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Nov 8, 20235 min read


What Is Sleep For?
Sleep is one of our basic biological functions. We'll talk about what it is, what it's for, and also 8 keys to a healthy sleep cycle.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Nov 2, 20236 min read


If You're Tired, Try This First.
If you're tired all the time, here are some factors to rule out at home or with your doctor.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Sep 22, 20236 min read


What is Fatigue, And Why Does Everyone Have It?
Fatigue, which is a feeling of extreme tiredness, weakness, or exhaustion, is the first symptom of almost every medical problem, including MTHFR. It can be linked to almost every body system, and it is the most general symptom we have. It is also linked to a number of common gene SNPs, including MTHFR, fast MAOA, fast COMT, and more. It is tied to lifestyle factors like diet, nutrition, sleep, and stress. So, actually, in light of all of that, it is surprising any of us don't

Dr. Amy Neuzil, Methylation and MTHFR Expert
Sep 18, 20235 min read
MTHFR and Migraine
As with so many other conditions, the research shows that people with the MTHFR gene mutation are more likely to have migraines....

Dr. Amy Neuzil, Methylation and MTHFR Expert
Aug 11, 20234 min read


The Problem With Blood Tests For Folate
Blood tests for folate have one big fatal flaw, making them both innaccurate and functionally useless, and the most common folate levels that we see on the blood tests of people with MTHFR might surprise you.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Jul 27, 20235 min read
10 Quick Tips for Balanced Blood Sugar with MTHFR
Blood sugar matters for everyone because it is linked to or at the root of the top three killers in the US. Balanced blood sugar matters...

Dr. Amy Neuzil, Methylation and MTHFR Expert
Jul 20, 20234 min read


Low Glycemic Index Diet For MTHFR
Glycemic index sounds highly unsexy, which is fair, but it's actually a diet hack that can help you to keep your blood sugars balanced with very little work. You don't even need to know the exact glycemic index of a particular food to understand how to use this system.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Jun 30, 20236 min read
bottom of page