Homocysteine

PEMT quietly works alongside MTHFR, and when both are affected, the impact on health can be much more significant. MTHFR and PEMT must be managed together to avoid consequences to fertility, liver function, neurotransmitters, and more.

Inflammation is a natural response by the body to injury or infection, but when it becomes chronic, it can contribute to many health problems. One factor linked to higher resting levels of inflammation is a genetic variation in the MTHFR gene. This post explores why MTHFR mutations may increase inflammation, reviews current research, and offers practical strategies to reduce inflammation naturally.

Blood clotting disorders can pose serious health risks, including stroke, deep vein thrombosis, and pulmonary embolism. One genetic factor that influences clotting risk is the MTHFR gene mutation

The connection between MTHFR gene mutations and blood clot risk often centers on homocysteine levels. The common story goes like this: if you have an MTHFR mutation, your homocysteine will be high, and that means you face a greater risk of blood clots. But this narrative oversimplifies a complex relationship.

High homocysteine is one of the most medically recognized consequences of having an MTHFR gene mutation, and learning to lower homocysteine with MTHFR can protect your health long-term. Balancing your methylation and boosting your B vitamins, especially B2, folate or 5-LMTHF, and B12, is the usual first step with MTHFR. But for true health, there are some other things that matter as well.

MTHFR and homocysteine are linked because homocysteine builds up when the folate cycle isn't working efficiently, which can happen with MTHFR. Because of this, testing homocysteine can be a helpful way to determine whether the health changes you are making for your MTHFR gene mutation are actually effective for you. In this post, we will cover Homocysteine testing and parameters - what is normal, what isn't, and what is considered normal but maybe shouldn't be.