The connection between MTHFR gene mutations and blood clot risk often centers on homocysteine levels. The common story goes like this: if you have an MTHFR mutation, your homocysteine will be high, and that means you face a greater risk of blood clots. But this narrative oversimplifies a complex relationship.

Blood tests for folate have one big fatal flaw, making them both innaccurate and functionally useless, and the most common folate levels that we see on the blood tests of people with MTHFR might surprise you.