There are a number of both risks and potential therapeutic effects that are worth considering with MTHFR and any form of medical or non-medical cannabis use. The primary considerations are addiction and addictive tendencies, medical risks for MTHFR specifically, and also cannabis and its derivatives as methylation adaptogens.

Castor oil has, in fact, been used for thousands of years and was considered so valuable it was included in the tombs of ancient Pharos in Egypt as early as 4,000 B.C.