The question "What does choline do" is a complex one. Once it enters the body, it can be directed toward several very different jobs. It can help build cell membranes, become the neurotransmitter acetylcholine, or e converted into betaine and contribute methyl groups to the methylation cycle.

PEMT quietly works alongside MTHFR, and when both are affected, the impact on health can be much more significant. MTHFR and PEMT must be managed together to avoid consequences to fertility, liver function, neurotransmitters, and more.