The idea that methyl folate could be a better option than folic acid in prenatal vitamins is controversial, because folic acid has been the fertility go-to treatment since it was discovered in the 1930s. The issue is, MTHFR had NOT been discovered in the 1930s, and the research hadn't really dived into the genetic needs of infertile couples yet.

5000 mcg folic acid is the standard recomendation for anyone struggling with low fertility, but current research evidence shows that 5000 mcg folic acid reduces fertility in people with the MTHFR gene mutation, and possibly in peopel without it as well.