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Before You Blame MTHFR: 10 Other Reasons Why Homocysteine Is High
You get your bloodwork back and your homocysteine is elevated. If you've ever looked at Instagram ever your first thought is probably "It must be MTHFR!" You might be right, especially if you have an MTHFR C677T variant, which is most closely associated with high homocysteine. But there are many other reasons for homocysteine to be elevated, so don't stop looking once you see MTHFR.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Sep 176 min read


The Hidden Dangers of High-Dose Vitamin B6: Identifying Toxicity Symptoms and Long-Term Effects
Vitamin B6 supports brain function, helps produce neurotransmitters, and assists in red blood cell formation. Because of these benefits, some people take supplements in doses far exceeding the recommended daily allowance (RDA), hoping to improve mood, reduce anxiety, or manage neuropathic pain. The RDA for adults is about 1.3 to 2 mg per day, but some supplements provide doses of 50 mg or more, sometimes reaching several hundred milligrams daily.

Dr. Amy Neuzil, Methylation and MTHFR Expert
Jan 83 min read


Vitamin B6, Folate Activation and Methylation Pathways
Vitamin B6 plays a critical role in several biochemical processes essential for health. One of its most important functions is supporting the activation of folate and facilitating methylation pathways. These processes are vital for DNA synthesis, gene expression, and overall cellular function

Dr. Amy Neuzil, Methylation and MTHFR Expert
Dec 18, 20253 min read
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