Staying asleep comes down to managing everything that would wake you up, like blood sugar, nighttime cortisol spikes, histamine, hormones, and pain. Supplements to stay asleep have to cover whichever of these problems you're struggling with. Let's talk about those things with the exception of pain, which is its giant topic, and very personal to the circumstance and type of pain.

Methylation is a very small, foundational chemical function in your body. It involves the moving of a methyl group, which is a carbon with three hydrogens that you can picture a lot like a Mickey Mouse head with an extra ear (shudder).

Sleep problems can be divided into four main categories based on the pattern of sleep disturbance that you experience. These patterns can help you narrow down some of the contributing factors in your sleep trouble.

Understanding fatigue means understanding what gives you the feeling of having energy in the first place.

Histamine and MTHFR are bound together for so many reasons. Histamine levels are affected by methylation, and histamine breakdown is methylation-dependent. Another big reason is that just like MTHFR, histamine has its fingers in so much more than just allergies.