MTHFR is well known for causing heart health issues. It’s directly responsible for raising homocysteine levels, it’s implicated in troublesome blood clotting, and it’s indirectly responsible for making it harder to make adequate nitric oxide. All of this is compounded…
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We haven’t discussed glutathione in a while, but MTHFR’s effects on glutathione production are of major consequence in the health of all of us MTHFR folks. While a sluggish methylation typically leads to a sluggish glutathione production, there are some…
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The COMT fast picture, as you can imagine, is the flip-side of COMT slow. This enzyme works too well, eliminating crucial substances before they have the chance to act. The most well researched polymorphism that contributes to this picture is…
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This week, let’s talk about our first of two COMT pictures. COMT slow. Remember, this means the COMT enzyme is less efficient than normal so the catecholamines it is supposed to break down stay in circulation longer. This leads to…
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To kick off our series on other polymorphisms, I’m starting with another heavy-hitter that is deeply entwined with MTHFR. This polymorphism is also in a gene that codes for an enzyme by the name of catechol-O-methyltransferase. I’m hoping that right…
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This week I want to start a mini-series of talks about other gene SNPs with or without MTHFR. I actually want to start it out with a disclaimer, and this is something that you’ve heard me say before, but it bears…
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Basic state is something that we’ve talked about before, but I want to dive a little bit deeper into why I feel it’s important when other fantastic practitioners, like Dr. Ben Lynch, aren’t really into it. Honestly, there is no…
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MTHFR and depression are intimately linked. We’ve spoken about this before, and if you want to brush up, take a look at Season 1 Episode 8 where we explored the link between the MTHFR mutation and neurotransmitter formation via the…
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This week, I’d like to get to some questions that listeners have been kind enough to leave on the website and within the community. The first comes from Liana O and she says “Specific 5-L-methyltetrahydrofolate supplement recommendations and dosing, please?”…
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